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Organoid-on-a-Chip Platform to Accelerate Personalized Drug Development

ABOUT US

Single-Cell Microfluidics and Advanced Technologies

Acoustic Bio is pioneering technologies that automate and scale patient-derived organoids (PDOs) screening for personalized drug development. Our innovative platform integrates microfluidics, live imaging, acoustic technology, and machine learning to deliver a first-in-class high-throughput Organoid-on-a-Chip screening platform. It is designed for small and large biotech and pharma, providing a cost-effective solution to generate large-scale data to better identify new drugs that will work in patients.

Organoid 3

Miniaturization

Transition from plate-based format to nanowell array microfluidic device to increase screening capacity by orders of magnitude

High-Throughput Screening

The platform allows massively parallel functional screening of thousands of single organoids

Patented Acoustic Technology

Innovative acoustic technology allows rapid retrieval of selected organoids for downstream multi-omics analysis to determine the mechanism of action

SIMPLIFY WORKFLOWS with
integrated system

Miniaturization, automation, and real-time imaging enables high-throughput assays on a microfluidic chip

PIONEERING SOLUTIONS

Extensive
Application Potential

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Preclinical Drug Development

High-throughput screening assays for lead identification using patient-derived organoids as predictive disease model

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Personalized Medicine

Predict stratification of patients into clinical trials and  identify which drugs are most effective for specific patient populations

Biomarker Discovery

Identify biomarkers that are associated with drug response by phenotypic and multi-omics analysis of organoids

CAR-T

Immunotherapy

Co-culture tumor organoids with engineered immune cells to monitor their interactions, such as cytotoxic potential

How it works

A powerful platform for high-throughput screening of patient-derived organoids

How Acoustic bio's technology works

INNOVATION IN ACTION

Retrieval for multi-omics analysis

Real-time video of acoustic retrieval of brain organoid

Acoustic Bio

MEET THE TEAM

We are a group of technologists working at the intersections of engineering and biology to build a novel platform to accelerate single-cell analysis. The team has extensive experience in commercialization of microfluidic imaging systems.

TEAM MEMBERS

Bahram Fathollahi, PhD
Founder and CEO

Daniel Stearns, PhD
Founder and CTO

Jay Whalen
Director of Engineering

David Peisley
Senior Systems Engineer

Matt Strain, MD, PhD
Vice President of Biology

Bahram Fathollahi, PhD Founder & CEO

  • 20+ years R&D leader in commercialization of Microfluidic Platforms, established partnership with pharma on technology adoption
  • Grew revenue from $25M to $150M. Caliper acquired by PerkinElmer for $750M
LinkedIn

Dan Stearns, PhD Founder & CTO

  • 25+ years R&D leader in commercialization of Biological Imaging Systems
  • Xenogen acquired by Caliper Lifesciences for $80M
LinkedIn

Jay WhalenDirector of Engineering

David PeisleySenior Systems Engineer

SCIENTIFIC ADVISORS

Ronald W. Davis, PhD
Professor of Biochemistry and Genetics, Stanford University

Dino Di Carlo, PhD
Professor and Vice Chair of Bioengineering, UCLA 

Richard Stearns, PhD
Principal Scientist

Join US

Career
Opportunities

Machine Learning Engineer
Interested in joining the team, reach out to learn more at info@acoustic.bio

Contact Us

We are open to explore strategic partnerships on the use of our platform for novel bioproduct discovery

Acoustic Bio, Inc.

319 Bernardo Ave. Mountain View, CA 94043